★★★★★ 943 REVIEWS

Never Feel The
Effects of Aging.

NESIS® fuses proven cognitive enhancers with essential botanicals, each selected for their scientifically-backed benefits to brain health. It's designed to promote sharper focus, enhanced memory, and sustained mental energy. No jitters. No fillers. Just pure cognitive empowerment.

BOOSTS ENERGY ELEVATES MOOD IMPROVES SLEEP MANAGES STRESS ZERO CRASH

"My mission is not to add years to your life but to help you add life to your years."

Our Founder

Dr. Kevin Bunting Jr., PharmD, Clinical Pharmacist

When I started on the journey to develop NESIS®, I dove deep into the science and literature of this term I saw everywhere - "nootropics."

After 4 years of exhaustive research and over ten formula iterations, NESIS® was born, supported by 187 peer-reviewed studies. I've ensured each ingredient is at or above the clinically effective dose, not just trace amounts for show.

Full Ingredient List

Full Ingredient List: Neuroprotective & Cognitive Small Molecules: L-Tyrosine, Acetyl-L-Carnitine, Alpha-GPC, Alpha-Lipoic-Acid, L-Theanine, Phosphatidylserine, EMLOM® Botanical Blend: Rosemary extract, Sage extract, Ashwagandha extract, Lemon Balm extract.

Other Ingredients: Vegetarian Capsule (microcrystalline cellulose, silicon dioxide, hypromellose)

No Artificial Additives

No GMOs, No Herbicides or Pesticides, No Artificial Colors, Flavors, Preservatives, Heavy Metals, or Neurotoxins

No Hidden Proprietary Blends

All labeling and dosing is transparent

Stay Sharp & Optimally Balanced

We've distilled the essence of cognitive enhancement, eliminating non-essentials, and incorporated advanced nootropics to optimize your mental performance and well-being.

0 mg caffeine per serving

cGMP Formulation

Seamless & Efficient

Designed for convenience and precision optimized with once-daily dosing in a straightforward, easy-to-manage regimen. Six capsules to deliver everything your brain needs to function at its best.

Feeling

Sharp, Balanced & Empowered

Achieve crystal-clear focus, enhanced memory, and a calm yet alert state. Boost your cognitive performance and feel equipped to conquer any challenge

Rigorously Tested

No-Skip-Lot Testing

Conducted on every single batch of NESIS® to ensure purity and potency as well as verification that each batch is free of heavy metals, neurotoxins and other contaminants.

Optimized Bioavailability

Our ingredients are not only synergistic with each other but also presented in a formulation to maximize oral bioavailability and absorption

No Fillers, Just Facts

No unnecessary fillers, just clinically researched ingredients in their optimal doses. NESIS® delivers what your brain needs to thrive, without compromise.

★★★★★ 943 REVIEWS

REAL CUSTOMERS, REAL RESULTS

Routine? Feelings? Results?

✅ Verified Purchase
I am in my late 20s and noticed a decline on my mental health. I've also noticed how often I easily stressed over the little things and constantly be very forgetful to the point my close family and friends would be concerned.

It took about 3 weeks for me to feel the full effect. I’m much more energized in the morning and throughout my 8-hr shifts. Before, I’d usually crash during lunch time and would have to drink another shot of espresso to keep me going. I also noticed that I’m way less irritable with things that usually annoy me. Not sure if it’s related but my skin has been less inflamed, I’ve always had hormonal acne and it gets worse when I’m stressed!
— Dr. Ellen L., Pharm.D. Clinical Pharmacist, Oncology
It was only the first dose and I felt like a goddess! As a physician, I was skeptical of any supplement improving qualities like cognition and focus. We learn so little about it in our training. However, there is reliable literature out there and it seems like Dr. Bunting did his homework. The first week of taking Nesis, I noticed a difference in my mental clarity and that eventually turned to better emotional regulation and awareness within my own mind after a few weeks of taking it. It's now a must in my morning routine!
— Dr. Brooke S., D.O. Ophthalmologist
I am a 64-year-old woman, committed to maintaining my health as I age. I take calcium daily for my bone health, so why wouldn’t I take something for my brain health as well? With both a paternal and maternal history of dementia and Alzheimer’s disease, prioritizing mental wellness and cognitive longevity is crucial for me. After starting Nesis, I've noticed a remarkable difference in how I feel day-to-day. The mental fog and scattered thoughts that used to cloud my days have significantly diminished.

I find myself being more present and engaged when spending time with my friends and family. There is truly nothing more fulfilling than enjoying meaningful interactions with my granddaughter, my children, and my wonderful partner. Nesis has not only improved my cognitive health but has enhanced the quality of my personal relationships, making every moment count.
— Debbie S., Pediatric Occupational Therapist
I’ve been taking Nesis now for 3 months and feel like I’ve reached an optimized level of productivity. My morning routine is to take 6 capsules with water and a cup of cold brew. I easily crush the next 4-5 hours and am getting pretty much everything I need to do for the day, done. I still work throughout the day, but I’m now free-thinking on new ideas, opportunities and concepts that interest me. I highly recommend Nesis as it has changed my life and there’s no going back!
— Brad N., Patent Attorney, Chemist and Business Owner

NESIS® IN THE WILD

The Doses That Give Benefits

THE DOSES THAT GIVE BENEFITS

L-Tyrosine | 2,000 mg

An amino acid essential for neurotransmitter synthesis that enhances mental alertness and mood regulation.

  • 100% pure L-isomer Tyrosine for optimal bioavailability.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 1.
THE DOSES THAT GIVE BENEFITS

Acetyl-L-Carnitine | 1,000 mg

A derivative of L-Carnitine that supports mitochondrial energy production and cognitive function. Renowned for its neuroprotective benefits.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 2.
THE DOSES THAT GIVE BENEFITS

Alpha GPC | 600 mg

A natural choline compound that boosts cerebral metabolism and aids cognitive function, especially memory and learning. Provides high bioavailability of choline.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 3.
THE DOSES THAT GIVE BENEFITS

Alpha-Lipoic-Acid | 350 mg

A potent antioxidant that helps protect neurons from oxidative stress and improves cellular energy production. Universally involved in cellular metabolism.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 4.
THE DOSES THAT GIVE BENEFITS

L-Theanine | 100 mg

An amino acid found in green tea that promotes relaxation without sedation. Enhances focus and sleep quality through modulation of excitatory neurotransmitters.

  • 100% pure L-isomer of Theanine

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 5.
THE DOSES THAT GIVE BENEFITS

Phosphatidylserine | 100 mg

A vital component of nerve cell membranes that enhances memory and cognitive capacity. Sourced for highest purity to support brain health.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 6.
THE DOSES THAT GIVE BENEFITS

Rosemary | 500 mg‡

Contains antioxidative and neuroprotective compounds like rosmarinic acid, enhancing cognitive function and memory. Clinically studied for its therapeutic effects.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 7.
THE DOSES THAT GIVE BENEFITS

Sage | 500 mg‡

Known for its cognitive-enhancing properties and ability to boost recall abilities and attention. Contains active ingredients that inhibit acetylcholinesterase.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 8.
THE DOSES THAT GIVE BENEFITS

Lemon Balm | 500 mg‡

An herb that aids in stress relief and cognitive performance by modulating GABA receptors. Supports a calm yet alert mental state.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 9.
THE DOSES THAT GIVE BENEFITS

Ashwagandha | 300 mg‡

An adaptogen that helps manage stress and enhances focus by regulating neurotransmitter systems. Studied for its potential to improve cognitive and neurological function.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 10.
THE DOSES THAT GIVE BENEFITS

L-Tyrosine | 2,000 mg

An amino acid essential for neurotransmitter synthesis that enhances mental alertness and mood regulation.

  • 100% pure L-isomer Tyrosine for optimal bioavailability.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 1.

Acetyl-L-Carnitine | 1,000 mg

A derivative of L-Carnitine that supports mitochondrial energy production and cognitive function. Renowned for its neuroprotective benefits.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 2.

Alpha GPC | 600 mg

A natural choline compound that boosts cerebral metabolism and aids cognitive function, especially memory and learning. Provides high bioavailability of choline.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 3.

Alpha-Lipoic-Acid | 350 mg

A potent antioxidant that helps protect neurons from oxidative stress and improves cellular energy production. Universally involved in cellular metabolism.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 4.

L-Theanine | 100 mg

An amino acid found in green tea that promotes relaxation without sedation. Enhances focus and sleep quality through modulation of excitatory neurotransmitters.

  • 100% pure L-isomer of Theanine

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 5.

Phosphatidylserine | 100 mg

A vital component of nerve cell membranes that enhances memory and cognitive capacity. Sourced for highest purity to support brain health.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 6.

Rosemary | 500 mg‡

Contains antioxidative and neuroprotective compounds like rosmarinic acid, enhancing cognitive function and memory. Clinically studied for its therapeutic effects.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 7.

Sage | 500 mg‡

Known for its cognitive-enhancing properties and ability to boost recall abilities and attention. Contains active ingredients that inhibit acetylcholinesterase.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 8.

Lemon Balm | 500 mg‡

An herb that aids in stress relief and cognitive performance by modulating GABA receptors. Supports a calm yet alert mental state.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 9.

Ashwagandha | 300 mg‡

An adaptogen that helps manage stress and enhances focus by regulating neurotransmitter systems. Studied for its potential to improve cognitive and neurological function.

Learn More

Rating of 1 means .
Rating of 10 means .
The rating of this product for "" is 10.

Us v. Them

NESIS
Leading Competitor
Generic Ingredients
Diet Alone
Cost per Serving
$3.23
$6.25
$5.43
Unknown
Capsules per Serving
6
2
17
N/A
Peer-Reviewed Referenced Articles
187
3
Unknown
N/A
Caffeine Content
0 mg
100 to 300 mg
0 mg
0 mg
Clinically-Researched Potencies
No
Rarely
No
Clinician Formulated
No
No
Rarely
Transparent Labeling without Proprietary Blends
No
Mostly
Mostly
Bioactive Compounds
Some
Yes
Mostly
Synergized Mechanisms to Improve Results
No
No
No
Sustainable Packaging Refill System
No
No
Rarely

What You Get

Month 1: Welcome Kit

$167 Value | $97 with subscription

Bio-Based Tray: Made of natural and renewable resources (sugarcane & sorghum pulp, water)

Reusable 500 mL Glass Jar: This is to cut down on harmful plastic waste on our planet and to keep costs lower for our customers as well. Keep this jar and simply refill every month.

Aluminum Travel Tin: It's easy to disrupt your routine when you travel - so, we designed a travel-tested aluminum tin that can easily fit in a carry-on or slide into a small pocket in a hiking backpack. Hardy enough not to break. Holds a 2-week supply (14 days) of NESIS

99-Page Hardcover Literature and Mechanism Book: An accumulation of four(4) years of work from our founder, Dr. Bunting, and his exhaustive literature review of 187 peer-reviewed articles, mechanisms of action breakdown and explanation of each ingredient on the molecular level.

30-Day Supply (180 Capsules): 180 capsules of NESIS® INCEPTION

Month 2: Sustainable Refill

Monthly Refills: 30 days supply sachet, delivered monthly with a smaller box and less shipping materials to reduce our footprint and keep costs as low as possible for our customers

NESIS /'nēsəs/

n. A philosophy that recognizes the inception of each physiological pathway as pivotal to achieving systemic equilibrium and enhanced functioning, advocating for targeted, foundational support through clinically researched formulations.

Cognition

Every thought, memory, and insight begins with a neuron. Nurture them.

Nootropic

/ no·o·trop·ic /ˌnōəˈträpik/

n. A class of cognitive-enhancing compounds that selectively confer upon the user improvements in the efficiency of neuronal systems, particularly those associated with executive functions, memory retrieval, creativity, and neuroplasticity, without the incurrence of deleterious side effects or neurophysiological dependency.

FAQs

Can I still drink coffee when I take NESIS?

Absolutely, since NESIS has zero (0) mg of caffeine, it is safe to consume your normal amount of daily caffeine.

How many capsules per serving?

Our clinically-researched formula is six (6) easy-swallow vegetarian capsules once daily

Do you recommend starting at the full serving?

Honestly, you know your body best. When we were testing our formula, our users fully tolerated the recommended serving. Also, each serving has been thoroughly researched to be safe and effective at these amounts*

If you are uncomfortable starting at the full serving, we recommend the following serving schedule:

Three (3) capsules once daily for days 1-3

Four (4) capsules once daily for days 4-6

Five (5) capsules once daily for days 7-9

Six (6) capsules once daily starting on day 10

Will NESIS interact with any of my medications or supplements I currently take?

Please speak to your local pharmacist or physician to clarify. We worked very hard to ensure these ingredients have the lowest number of interactions and contraindications, however, this falls into a case-by-case basis.

How is NESIS best taken?

We recommend taking this once daily on an empty stomach upon awakening. Taking this with your morning tea or coffee is OK.

I have diabetes. Is NESIS safe for me to take?

A few of our ingredients have been shown to improve insulin sensitivity and suppress gluconeogenesis (production of glucose), therefore may lower blood glucose levels and should be monitored. It is best to speak with your primary physician helping manage your glucose levels to ensure this product is safe for you.

I have a seizure disorder. Is NESIS safe for me to take?

Please speak to your neurologist regarding NESIS supplementation. They will be able to help guide based on your specific seizure disorder (i.e. tonic-clonic, absence, etc.)

What happens if I miss a serving?

If you remember within 8 hours of your normal time to take NESIS INCEPTION, you are OK to take the missed serving.

Example: Normal serving time: NESIS at 0600, remember at lunchtime, OK to take

Example: Normal serving time: NESIS at 0600, remember at dinnertime, SKIP and restart regimen on the following day

NOTE: The reason we tell you to skip the serving is not because of safety issues, it's more related to the idea that you want to take NESIS INCEPTION at the start of your day when you're most alert, not when you're about to unwind and maintain good sleep hygiene.

How long until I start to feel the effects and experience the benefits of NESIS?

Overall, you may start to feel the effects the first morning you take NESIS - between 30-60 minutes.

You should see a bit of a cycle at first while your body is reaching what we call a "steady state" in pharmacokinetic terms. This means your body is maintaining an equilibrium of the molecules within the desired levels.

The cycle may look something like this:
Day 1-5: Relative and noticeable increases in your drive, endurance, memory, focus

Day 6+: Your new baseline which may not "feel" as drastic of a change, but has become the new "flow" state for your functionality

Remember, this product is working at the cellular level, and unlike compounds like caffeine, this should not leave you with jittery jolts followed by a massive crash. The goal is an optimized state of being that is steady and sustainable

Does NESIS contain caffeine? Will I crash midway throughout my day?

NO, there is no caffeine in NESIS therefore, once you reach a steady state, (see FAQ question "How long until I start to feel the effects and experience the benefits of NESIS?" for a definition on steady state) you should have a new baseline energy and efficiency at the cellular level.

Do I take NESIS everyday or just on the days I need a "mental boost?"

You should be taking NESIS daily. In reality, it's only our first four (4) ingredients (L-tyrosine, acetyl-L-carnitine, alpha GPC, and alpha-lipoic acid) that should yield any perceived feelings up front. The remaining six (6) ingredients target more along the chronic stress pathways and chronic systemic inflammation pathways.

In other words, you taking NESIS PRN (as needed) will only give you short-term benefits. If you'd like to optimize to the complete vision of NESIS and also seek out cognitive longevity benefits, we recommend daily use.

My urine sometimes smells like asparagus after taking NESIS. Is this normal?

Yes. The ingredient alpha GPC is a precursor to the molecule choline. If you happen to drink less fluids one day, choline levels may increase and concentrate in the urine during the excretion process and resemble the scent of asparagine (the amino acid responsible for the scent after you eat asparagus).

†THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FDA. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.
‡ Equivalent from 500 mg of concentrated Rosemary, Sage and Lemon Balm and 300 mg of concentrated Ashwagandha extracts.