About Us

NESIS® was founded with the mission of creating the best in class health & longevity products. Our philosophy is to take a novel approach to supplement formulation: to analyze the begining (the genesis) of biochemical pathways and understand the points in which these pathways breakdown, thus yielding a break in homeostasis.

You will never see a NESIS® product that brings you hyperbolic claims. We removed the "GE" from the name genesis to bring you a new beginning and philosophy on health & wellness. The body is complex and requires extensive levels of nuance.

Our Approach

Our approach is to understand the entire picture of longevity. The human body, and the enzymes within are some of the most complex machines and mechanisms in the known universe. We recognize that there is no "quick-fix" to any underlying condition. This is why we dedicate our expertise into understanding how multiple mechanisms can synergize to yield the desired effects and benefits. We also recognize that with our multifaceted approach is one of the largest contributing factors to sustainable longevity. 

Our Philosophy

Our philosophy came from a place of experience, and now comes from a place of expertise. We believe that prevention and a holistic approach (meaning whole human) is the only way to attain true longevity. We believe that if we can successfully analyze and account for the numerous iterations between one's own psychology and physiology, as a whole, we can make a true difference. 

Our Formulation Process

1. Null Hypothesis (Ho): The system (human) is better without ingredient x
2. Data Analysis: Research and evaluate all available literature - from large-scale clinical trials to anecdotal data (typically 100+ papers per ingredient)
3. Safety & Efficacy Analysis: We then take a deep dive on the risk v benefits profile of every single ingredient
4. Practical Integration: This is our secret step - How does each ingredient fit into the user's daily life?
• Using antidepressant medications called selective serotonin reuptake inhibitors (SSRIs) - one major side effect is decreased libido. Now, taking this into consideration, a psychiatrist would need to evaluate with the patient the risk v benefit of the SSRI.
• With NESIS® we do this same analysis. As an example, we were analyzing the ingredient St. John's Wart for decreased feelings of anxiousness. This ingredient has data suggesting it's effectiveness in this space, however, the drug-drug interactions of this strong CYP-inducer make it high risk and low benefit as a whole. We looks intentionally at this step and is often the longest step in our formulation process
5. Clinical Dosing & Potency: What is the minimum effective dose (MED) and is this does practical to place in a capsule or tablet?
6. Initial Testing: Most companies will use this step to test the ingredients themselves. We begin by testing each ingredient internally and focus group small batches of our formulations. This process typically takes 3-6 months of continuous and consistent use.
7. Formulation Iteration: Based on the direct feedback of step 6 we either continue or reformulate until we achieve the desired results.
8. Sourcing, Purity, & Manufacturing: We only source the highest quality ingredients from our cGMP facility in New York, USA.
9. Post Marketing Analysis: We continuously monitor results, receive feedback and modify our formulas as needed based on the results.